Description

AOD9604

AOD9604 is a high-purity synthetic peptide fragment derived from the C-terminus of the human Growth Hormone (hGH) molecule, specifically encompassing amino acids 177 through 191. In the landscape of advanced metabolic research, AOD9604 is distinguished by its highly specific lipolytic (fat-burning) properties. Unlike the full-length hGH molecule, AOD9604 is engineered to isolate the metabolic benefits of the parent hormone while eliminating unwanted side effects; it does not stimulate growth, nor does it adversely impact blood glucose levels or insulin sensitivity. Its primary mechanism involves the stimulation of fat metabolism by mimicking the way natural hGH regulates lipid oxidation. It provides researchers with a high-precision experimental model to investigate the treatment of obesity, the reduction of localized adipose tissue, and the molecular pathways of cartilage repair and bone metabolism.

Our AOD9604 is synthesized in an ISO 9001:2015 certified environment utilizing high-precision Solid-Phase Peptide Synthesis (SPPS). We achieve an ultra-high chemical purity of ≥99%, verified by HPLC and Mass Spectrometry (MS). This rigorous production standard ensures the peptide is free from truncated sequences and residual chemical catalysts, guaranteeing the consistency and structural fidelity required for high-stakes metabolic signaling and musculoskeletal regeneration research.

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Research Applications & Mechanisms

Enhanced Lipolysis & Fat Metabolism

Investigating the upregulation of lipid oxidation and studying the peptide’s role in triggering the release of fat from experimental obese fat cells.

Metabolic Safety & Glucose Homeostasis

Researching the unique pathway through which AOD9604 promotes fat loss without the hyperglycemic risks associated with full-spectrum growth hormone research.

Chondrogenic & Cartilage Repair

Studying the mechanisms through which AOD9604 supports the regeneration of cartilage tissue and its potential role in investigating systemic bone health.

Beta-3 Adrenergic Receptor Interaction

Exploring the impact of AOD9604 on adipose tissue receptors to research the optimization of systemic metabolic rates in diverse research designs.

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Technical Specifications

Parameter	Laboratory Standard
Compound	AOD9604 (hGH Fragment 177-191)
Sequence	Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
Purity (HPLC)	≥99% (Pharmaceutical Grade)
Physical Appearance	Fine, Smooth & Flat Lyophilized Cake
Molecular Weight	1815.1 Da
Concentrations	Available in 2mg, 5mg, 10mg vials
Solubility	Highly Soluble in Water (Aqueous) / Bacteriostatic Water
Batch Control	MS & HPLC Analysis Verified

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Key Features & Quality Assurance

Pharmaceutical-Grade Lyophilization

Our proprietary vacuum-sealing process ensures the AOD9604 powder surface is perfectly smooth, flat, and delicate. This uniform “cake” structure ensures rapid, clear reconstitution and maintains the molecular stability of the 15-amino acid fragment during storage.

High-Fidelity C-Terminus Integrity

Every batch undergoes strict Mass Spectrometry (MS) to confirm the exact amino acid sequence, ensuring maximal receptor binding affinity and reproducible results in complex lipolytic signaling assays.

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Reconstitution & Storage

Reconstitution Guide

• Preparation: Allow the vial to reach room temperature. Centrifuge for 30-60 seconds to ensure the AOD9604 cake is at the base.

• Solvent: Reconstitute with Sterile Water or Bacteriostatic Water.

• Technique: Gently introduce the diluent against the vial wall. DO NOT SHAKE; swirl gently until the solution is clear and transparent.

Storage Protocols

• Long-term: Store at -20°C (Maintains potency for up to 24 months).

• Short-term: Stable at 2–8°C for up to 3 months.

• Post-Reconstitution: Store at 2–8°C and utilize within 10-14 days for optimal results.

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Shipping & Documentation

• Global Logistics: Shipped in discreet, temperature-controlled packaging to maintain the structural integrity of the AOD9604 peptide.

• Verified Quality: A batch-specific COA and HPLC/MS reports are available for every order.

• Reshipment Policy: We provide a guaranteed reshipment policy for any lost or customs-intercepted orders (terms apply).

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⚠️ Research Disclaimer

Product-Specific Safety Notice: This AOD9604 is strictly for laboratory research and analytical purposes. It is NOT intended for human or veterinary administration. All research must be conducted by qualified professionals.

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Scientific Resources & References

• National Center for Biotechnology Information (NCBI): AOD9604 Compound Summary & Metabolic Research

• ScienceDirect (Elsevier): Peer-reviewed Research on hGH Fragments and Lipolysis

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🔍 Deep Dive Research

• [Technical Guide]: How to Reconstitute and Store Lyophilized Peptides for Maximum Potency

• [Metabolic Study]: Targeting the Fat: The Science of AOD9604 in Modern Obesity Research