Description

Cardiogen (AEDR)

Cardiogen (scientifically identified by the amino acid sequence Ala-Glu-Asp-Arg or AEDR) is a high-purity synthetic tetrapeptide. In the field of advanced cardiovascular medicine and regenerative biology, Cardiogen is recognized as a tissue-specific bioregulator for the heart and vascular system. Its primary mechanism of action involves the modulation of gene expression and protein synthesis within cardiomyocytes and vascular endothelial cells. It provides researchers with a high-precision experimental tool to investigate the restoration of heart muscle structural integrity, the mitigation of fibrotic tissue formation, and the promotion of metabolic homeostasis within the cardiovascular network. Cardiogen is widely utilized in studies focusing on age-related cardiac decline and the molecular pathways of post-ischemic recovery.

Our Cardiogen (AEDR) is synthesized in an ISO 9001:2015 certified environment utilizing high-resolution Solid-Phase Peptide Synthesis (SPPS). We achieve an ultra-high chemical purity of ≥99%, verified by HPLC and Mass Spectrometry (MS). This rigorous production standard ensures the tetrapeptide is free from truncated sequences and residual synthesis reagents, guaranteeing the consistency and structural fidelity required for sensitive cardiac assays and longitudinal cardiovascular health research.

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Research Applications & Mechanisms

Myocardial Protection & Regeneration

Investigating the mechanisms through which Cardiogen promotes the synthesis of tissue-specific proteins necessary for heart muscle repair and cardiomyocyte survival.

Modulation of Cardiac Fibrosis

Researching the influence of AEDR on preventing the excessive accumulation of connective tissue (fibrosis) in research models of cardiac stress or injury.

Vascular Endothelial Health & Microcirculation

Studying the peptide’s ability to normalize endothelial function and investigate the optimization of systemic and localized microvascular blood flow.

Gene Expression in Cardiovascular Aging

Exploring the impact of Cardiogen on the epigenetic regulation of cardiac cells to research the restoration of healthy physiological parameters in aged biological systems.

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Technical Specifications

Parameter	Laboratory Standard
Compound	Cardiogen (AEDR)
Sequence	Ala-Glu-Asp-Arg
Purity (HPLC)	≥99% (Pharmaceutical Grade)
Physical Appearance	Fine, Smooth & Flat Lyophilized Cake
Molecular Weight	489.48 g/mol
Concentration	Available in 20mg vials
Solubility	Highly Soluble in Water (Aqueous) / PBS
Batch Control	MS & HPLC Analysis Verified

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Key Features & Quality Assurance

Pharmaceutical-Grade Lyophilization

Our proprietary vacuum-sealing process ensures the Cardiogen powder surface is perfectly smooth, flat, and delicate. This uniform “cake” structure ensures rapid, clear reconstitution and maintains the molecular stability of the tetrapeptide during long-term storage.

High-Fidelity Sequence Integrity

Every batch undergoes strict Mass Spectrometry (MS) to confirm the exact amino acid sequence (Ala-Glu-Asp-Arg), ensuring maximal target specificity and reproducible results in complex cardiovascular signaling research.

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Reconstitution & Storage

Reconstitution Guide

• Preparation: Allow the vial to reach room temperature. Centrifuge for 30-60 seconds to ensure the Cardiogen cake is at the base.

• Solvent: Reconstitute with Sterile Water or PBS.

• Technique: Gently introduce the diluent against the vial wall. DO NOT SHAKE; swirl gently until the solution is clear and transparent.

Storage Protocols

• Long-term: Store at -20°C (Maintains potency for up to 24 months).

• Short-term: Stable at 2–8°C for up to 3 months.

• Post-Reconstitution: Store at 2–8°C and utilize within 14-21 days for optimal results.

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Shipping & Documentation

• Global Logistics: Shipped in discreet, temperature-controlled packaging to maintain the structural integrity of the Cardiogen peptide.

• Verified Quality: A batch-specific COA and HPLC/MS reports are available for every order.

• Reshipment Policy: We provide a guaranteed reshipment policy for any lost or customs-intercepted orders (terms apply).

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⚠️ Research Disclaimer

Product-Specific Safety Notice: This Cardiogen (AEDR) is strictly for laboratory research and analytical purposes. It is NOT intended for human or veterinary administration. All research must be conducted by qualified professionals.

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Scientific Resources & References

• National Center for Biotechnology Information (NCBI): Bioregulatory Peptides and Cardiovascular Research

• ScienceDirect (Elsevier): Peer-reviewed Research on Short Peptides and Myocardial Protection

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🔍 Deep Dive Research

• [Technical Guide]: How to Reconstitute and Store Lyophilized Peptides for Maximum Potency

• [Cardiovascular Study]: Protecting the Pulse: The Science of Cardiogen in Modern Heart Research