Description
HGH Fragment 176-191
HGH Fragment 176-191 is a high-purity synthetic peptide representing the C-terminal end of the human Growth Hormone molecule (amino acids 176–191). In the field of advanced metabolic and adipose tissue research, this fragment is highly distinguished by its ability to isolate the lipolytic (fat-burning) properties of HGH without the associated effects on insulin resistance or cellular growth (mitogenesis). Unlike the full-length hormone, HGH Frag 176-191 does not compete for the HGH receptor, thereby avoiding increases in blood glucose or IGF-1 levels. It provides researchers with a high-precision experimental model to investigate the stimulation of fat breakdown, the inhibition of lipogenesis, and the regulation of metabolic pathways in specialized obesity and energy expenditure studies.
Our HGH Fragment 176-191 is synthesized in an ISO 9001:2015 certified environment utilizing high-resolution Solid-Phase Peptide Synthesis (SPPS). We achieve an ultra-high chemical purity of ≥99%, verified by HPLC and Mass Spectrometry (MS). This rigorous production standard ensures the peptide is free from truncated sequences and residual synthesis reagents, guaranteeing the consistency and structural fidelity required for sensitive metabolic research.
Research Applications & Mechanisms
Stimulated Lipolysis & Beta-Adrenoceptors
Investigating the mechanism through which the fragment triggers the breakdown of triglycerides into free fatty acids in adipose tissue models.
Inhibition of Lipogenesis
Researching the peptide’s ability to inhibit the transformation of non-fatty materials into body fat (lipogenesis) in experimental metabolic designs.
Metabolic Syndrome & Adipose Regulation
Studying the influence of HGH Frag 176-191 on lipid profiles and systemic energy balance without impacting glucose tolerance or insulin sensitivity.
Cartilage & Connective Tissue Research
Exploring emerging data on the peptide’s potential role in promoting the repair of chondrocytes and maintaining the integrity of connective tissues.
Technical Specifications
| Parameter | Laboratory Standard |
| Compound | HGH Fragment 176-191 |
| Sequence | Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe |
| Purity (HPLC) | ≥99% (Pharmaceutical Grade) |
| Physical Appearance | Fine, Smooth & Flat Lyophilized Cake |
| Molecular Weight | 1815.1 Da |
| Concentrations | 1mg, 2mg, 5mg, 10mg, 12mg, 15mg per vial |
| Solubility | Soluble in Water / PBS / Bacteriostatic Water |
| Batch Control | MS & HPLC Analysis Verified |
Key Features & Quality Assurance
Pharmaceutical-Grade Lyophilization
Our proprietary vacuum-sealing process ensures the HGH Frag 176-191 powder surface is perfectly smooth, flat, and delicate. This uniform “cake” structure ensures rapid, clear reconstitution and protects the structural integrity of the sequence during storage.
Selective Metabolic Fidelity
Our synthesis ensures the exclusion of the GHR-binding domains found in full-length HGH, guaranteeing that your research focus remains purely on lipid metabolism without glycemic interference.
Reconstitution & Storage
Reconstitution Guide
-
Preparation: Allow the vial to reach room temperature. Centrifuge for 30-60 seconds to ensure the HGH Frag cake is at the base.
-
Solvent: Reconstitute with Sterile Water or Bacteriostatic Water.
-
Technique: Gently introduce the diluent against the vial wall. DO NOT SHAKE; swirl gently until the solution is clear and transparent.
Storage Protocols
-
Long-term: Store at -20°C (Maintains potency for up to 24 months).
-
Short-term: Stable at 2–8°C for up to 3 months.
-
Post-Reconstitution: Store at 2–8°C and utilize within 10-14 days for optimal results.
Shipping & Documentation
-
Global Logistics: Shipped in discreet, temperature-controlled packaging to maintain the structural integrity of the HGH Fragment 176-191 peptide.
-
Verified Quality: A batch-specific COA and HPLC/MS reports are available for every order.
-
Reshipment Policy: We provide a guaranteed reshipment policy for any lost or customs-intercepted orders (terms apply).
⚠️ Research Disclaimer
Product-Specific Safety Notice: This HGH Fragment 176-191 is strictly for laboratory research and analytical purposes. It is NOT intended for human or veterinary administration. All research must be conducted by qualified professionals.
Scientific Resources & References
- Structural, biochemical, and lipolysis-related research data for HGH Fragment 176-191 (AOD-9604) can be accessed via PubChem.
- Experimental pharmacology, peptide classification, and metabolic research context for HGH Fragment 176-191 are available through DrugBank.
🔍 Deep Dive Research
-
[Technical Guide]: How to Reconstitute and Store Lyophilized Peptides for Maximum Potency
-
[Metabolic Study]: Targeted Fat Metabolism: The Science Behind HGH Fragment 176-191
Reviews
There are no reviews yet.