PT-141 (Bremelanotide Acetate) – 10mg

$69.00

Compound: PT-141 (Bremelanotide Acetate) Components: Cyclic Heptapeptide Melanocortin Receptor Agonist Purity: ≥ 99% (Pharmaceutical Grade / HPLC & MS Tested) Form: Lyophilized White Powder (Vacuum Sealed) Solubility: Highly Soluble in Water (Aqueous) / Bacteriostatic Water Storage: 2-8°C (Short-term) | -20°C (Long-term / Up to 24 months) ⚠️ For Research Use Only. Not for human or veterinary applications. 

Description

PT-141 (Bremelanotide Acetate)

PT-141 (scientifically identified as Bremelanotide Acetate) is a high-purity synthetic peptide derivative of Melanotan II. In the domains of neurobiology and sexual medicine research, PT-141 is classified as a non-selective melanocortin receptor agonist. Unlike traditional phosphodiesterase-5 (PDE5) inhibitors that act directly on the vascular system, PT-141 is designed to exert its effects primarily through the central nervous system. Its primary research focus involves the activation of melanocortin receptors (specifically MC3R and MC4R) within the hypothalamus to modulate biological pathways associated with arousal and physiological response. PT-141 provides researchers with a sophisticated experimental tool to investigate the neuroendocrine mechanisms of sexual dysfunction and the systemic regulation of appetitive behavior.

Our PT-141 (Bremelanotide Acetate) is synthesized in an ISO 9001:2015 certified environment utilizing high-precision Solid-Phase Peptide Synthesis (SPPS). We achieve an ultra-high chemical purity of ≥99%, verified by HPLC and Mass Spectrometry (MS). This rigorous production standard ensures the peptide is free from truncated sequences and residual chemical reagents, guaranteeing the consistency and structural fidelity required for long-term neurochemical assays and physiological signaling studies.

pt141_peptide_Vial


Research Applications & Mechanisms

Central Nervous System Modulation

Investigating the activation of melanocortin receptors (MC3R and MC4R) within the paraventricular nucleus of the hypothalamus. Research focuses on the peptide’s ability to bypass the vascular system and act directly on the neural pathways that govern sexual desire and arousal responses.

Neuroendocrine Signaling & Pathways

Exploring the downstream effects of MC4R activation on dopaminergic signaling. Researchers utilize PT-141 to study the interplay between melanocortins and the brain’s reward and motivation circuits in various biological models.

Management of Hypoactive Sexual Desire (HSDD)

Researching the mechanisms through which cyclic peptide analogs normalize physiological responses in female and male research models. This includes studying the peptide’s role in restoring responsiveness to natural biological stimuli in immunocompromised or hormonally imbalanced systems.

Systemic Homeostasis & Receptor Affinity

Studying the binding affinity and selectivity of PT-141 across the melanocortin receptor family. This involves investigating its systemic impact on blood pressure, metabolic rate, and the subsequent regulation of tissue-specific responses to environmental and physiological stressors.

Technical Specifications

Parameter Laboratory Standard
Manufacturing Standard ISO 9001:2015 Certified Facility
Production Quality GMP-Level Compliance
Purity (HPLC) ≥99% (Pharmaceutical Grade)
Physical Appearance Fine, Smooth & Flat Lyophilized Cake
Form Lyophilized White Powder (Vacuum Sealed)
Solubility Highly Soluble in Water / Bacteriostatic Water
Batch Control MS & HPLC Analysis Verified
Filtration 0.22 μm sterile filtered

Key Features & Quality Assurance

  • Pharmaceutical-Grade Lyophilization: Our proprietary vacuum-sealing and freeze-drying process ensures the powder surface is perfectly smooth, flat, and delicate. This uniform “cake” structure guarantees rapid reconstitution and protects the peptide from degradation.

  • ISO 9001 Quality Management: Every production cycle follows a rigorous quality management system to ensure that the chemical identity of every batch is precisely as specified.

  • GMP Compliance: Manufactured in a sterile, clean-room environment to eliminate cross-contamination, providing the batch-to-batch consistency essential for reproducible research.

  • Verified Stability: The cyclic structure of our Bremelanotide Acetate is optimized for maximum stability and receptor binding affinity.


Reconstitution Guide (Important)

To ensure the maximum stability and integrity of the peptide, please follow these laboratory guidelines:

  • Preparation: Allow the vial to reach room temperature before reconstitution. Center the vial in a centrifuge for 30-60 seconds to ensure the lyophilized cake is at the bottom.

  • Solvent Selection: Reconstitute with Sterile Water for Injection or Bacteriostatic Water (0.9% Benzyl Alcohol).

  • Technique: Gently inject the diluent along the side of the vial wall. DO NOT SHAKE the vial; instead, gently swirl it until the solution is clear and colorless.

  • Concentration: We recommend a standard research concentration of 10mg/mL.


Storage & Handling

  • Long-term: Store at -20°C (Maintains potency for up to 24 months).

  • Short-term: Stable at 2–8°C for up to 3 months.

  • Reconstitution: We recommend centering the vial in a centrifuge before opening. Reconstitute using sterile or bacteriostatic water. The high-solubility lyophilized powder should yield a clear, colorless solution in seconds.


Shipping & Documentation

  • Global Logistics: Shipped in temperature-controlled, discrete packaging to ensure privacy and product security.

  • Verified Quality: A batch-specific Certificate of Analysis (COA), including HPLC and Mass Spectrometry (MS) reports, is available for every order.

  • Reshipment Policy: We provide a guaranteed reshipment policy for any lost or customs-intercepted orders (terms apply).


⚠️ Research Disclaimer

For Laboratory Research and Analytical Purposes Only. PT-141 is NOT a drug, food, or cosmetic and is strictly not intended for human or veterinary consumption. Handling and use must be performed by qualified laboratory professionals in accordance with standard safety protocols.


Scientific Resources & References


🔍 Deep Dive Research

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Additional information

Specification

10mg*10vials

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