Description

Tesamorelin

Tesamorelin Acetate is a potent synthetic peptide and a stabilized analog of the human Growth Hormone-Releasing Factor (GRF). Composed of a 44-amino acid sequence with a hexenoyl moiety attached to the N-terminal tyrosine, it is specifically engineered for advanced laboratory research into growth hormone signaling and adipose tissue metabolism. In research environments, Tesamorelin is widely investigated for its ability to stimulate the pituitary gland to synthesize and release endogenous growth hormone (GH), providing a precise model for studying lipolysis, insulin-like growth factor 1 (IGF-1) regulation, and metabolic syndrome pathways.

Our Tesamorelin Acetate is synthesized in an ISO 9001:2015 certified and GMP-grade manufacturing environment. Utilizing state-of-the-art Solid-Phase Peptide Synthesis (SPPS) and multi-stage HPLC purification, we achieve an ultra-high chemical purity of ≥99%. This meticulous production process ensures that the compound is free from truncated peptide fragments and residual reagents, guaranteeing the stability and accuracy required for high-stakes metabolic and endocrinology studies.

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Research Applications & Mechanisms

GHRH Pathway Modulation

Investigating the direct stimulation of pituitary somatotrophs to study the downstream effects of pulsatile growth hormone release.

Adipose Tissue Metabolism

Researching the peptide’s influence on lipolysis and the reduction of visceral adipose tissue (VAT) in experimental metabolic models.

IGF-1 Signaling & Homeostasis

Studying the correlation between Tesamorelin administration and the modulation of hepatic IGF-1 levels in various biological microenvironments.

Neurocognitive & Aging Research

Exploring the potential neuroprotective effects of GHRH analogs and their influence on cognitive markers in aging research models.

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Technical Specifications

Parameter	Laboratory Standard
Compound	Tesamorelin Acetate
Production Quality	GMP-Level Compliance
Purity (HPLC)	≥99% (Pharmaceutical Grade)
Physical Appearance	Fine, Smooth & Flat Lyophilized Cake
Molecular Formula	C221H366N72O67S
Molecular Weight	5135.9 Da
Solubility	Highly Soluble in Water (Aqueous) / Bacteriostatic Water
Batch Control	MS & HPLC Analysis Verified

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Key Features & Quality Assurance

Pharmaceutical-Grade Lyophilization

Our proprietary vacuum-sealing process ensures the Tesamorelin Acetate powder surface is perfectly smooth, flat, and delicate. This uniform “cake” structure optimizes reconstitution and prevents the 44-amino acid chain from oxidative degradation.

Superior Chemical Stability

By utilizing an acetate salt form and vacuum sealing, we ensure the structural fidelity of the peptide is maintained throughout shipping and long-term storage.

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Reconstitution & Storage

Reconstitution Guide

• Preparation: Allow the vial to reach room temperature. Centrifuge for 30-60 seconds to ensure the Tesamorelin cake is at the base.

• Solvent: Reconstitute with Sterile Water or Bacteriostatic Water.

• Technique: Gently introduce the diluent along the side of the vial. DO NOT SHAKE; swirl gently until the solution is clear and transparent.

Storage Protocols

• Long-term: Store at -20°C (Maintains potency for up to 24 months).

• Short-term: Stable at 2–8°C for up to 3 months.

• Post-Reconstitution: Store at 2–8°C and utilize within 7-14 days.

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Shipping & Documentation

• Global Logistics: Shipped in discreet, temperature-controlled packaging to protect the Tesamorelin molecular structure.

• Verified Quality: A batch-specific COA and HPLC/MS reports are available for every order.

• Reshipment Policy: We provide a guaranteed reshipment policy for any lost or customs-intercepted orders (terms apply).

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⚠️ Research Disclaimer

Product-Specific Safety Notice: This Tesamorelin Acetate is strictly for laboratory research and analytical purposes. It is NOT intended for human or veterinary administration. All research must be conducted by qualified professionals in controlled environments.

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Scientific Resources & References

• National Center for Biotechnology Information (NCBI): Tesamorelin Compound Summary (CID 16137828)

• American Chemical Society (ACS): Official CAS Search for GHRH Analogs (CAS RN: 218949-48-5)

• ScienceDirect (Elsevier): Peer-reviewed Research on Tesamorelin and Lipodystrophy Models

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🔍 Deep Dive Research

• [Technical Guide]: How to Reconstitute and Store Lyophilized Peptides for Maximum Potency

• [Metabolic Study]: The Role of GHRH Analogs in Adipose Tissue Redistribution Research